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Symbol
Name
ID

Jag1
jagged 1
MGI:1095416

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Stroke	Spina bifida occulta	Delayed speech and language development	Intellectual disability, mild	Areflexia	Severe global developmental delay	Specific learning disability
Disease(s) Associated with JAG1
Alagille syndrome

Mouse Phenotypes

intracranial hemorrhage

abnormal neuron differentiation

abnormal neural tube morphology

kinked neural tube

abnormal cochlear hair cell morphology

abnormal cochlear hair cell number

absent cochlear hair cells

decreased cochlear outer hair cell number

absent cochlear outer hair cells

increased cochlear inner hair cell number

abnormal cochlear outer hair cell morphology

absent vestibular hair cells

decreased neuronal precursor cell number

increased neuron number

Availability

Mouse Genotype

Jag1^Mhdahtu/Jag1^Mhdahtu

Jag1^Ndr/Jag1^Ndr

Jag1^Slalom/Jag1^Slalom

Jag1^tm2.1Grid/Jag1^tm2.1Grid

Jag1^Mhdahtu/Jag1⁺

Jag1^Slalom/Jag1⁺

Jag1^Yo/Jag1⁺

Jag1^tm1Jlew/Jag1^tm1Jlew (conditional)

Jag1^tm1Grid/Jag1^tm2Grid
Foxg1^tm1(cre)Skm/Foxg1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23